DESCRIPTION
How effective is Liporase Hyaluronidase?
This product can reverse the effects of Hyaluronic Acid fillers and boost those of fat-melting serums. Both of these applications of Liporase lead to almost immediate results because this enzyme starts to work the moment it is injected in the target area regardless if the latter is a fat deposit or a layer of the skin. However, with some HA filler injections, the effects may become visible 24-48 hours after it has been administered when the HA gel concentration or the cross-linking ratio is higher than the average.
How to apply it?
- Mix 1 vial with saline water (3cc to breakdown HA or 5cc to use it with a fat-melting injection)
- Administer local anesthetics to reduce discomfort during treatment
- Inject the solution into or around the target site
- Gently massage the treated area for a few minutes
- Schedule a follow-up appointment 2-3 weeks after the injection for a review
Important safety information
Patients who are not suitable candidates for treatment with Liporase Hyaluronidase are those who are:
- Allergic to Hyaluronidase or Hyaluronate
- Suffering from inflammation affecting the injection site
- Battling a local infection
This HA reverse agent is not to be injected into the veins or used topically.
Hyaluronidase is an enzyme (compounded by special pharmacies) that causes hydrolysis (breakdown) of hyaluronic acid. It is often referred to as a reversal agent for hyaluronic acid fillers. When the enzyme is injected it dissolves the synthetic hyaluronic acid filler, leaving your own intact. Liporase Hyaluronidase is made in Korea. It is used to dissolve hyaluronic acid based dermal fillers that have been placed incorrectly, excessively, or unevenly.
Liporase can be used to dissolve Dermal Fillers or to maximise the strength of lipodissolve injections. Liporase, also knowns as Hyaluronidase, is a tissue modifier indicated as an adjuvant in subcutaneous fluid administration for achieving hydration, to increase the dispersion and absorption of other injected drugs, and in subcutaneous urography for improving resorption of radiopaque agents.
Important Info:
- Those with hypersensitivity to hyaluronidase or any other ingredient in the formulation is not allowed to use this product
- Discontinue recombinant (hyaluronidase human injection) if sensitization occurs.
- Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs.
- Hyaluronidase should not be injected into or around an infected or acutely inflamed area because of the danger of spreading a localized infection.
- Hyaluronidase should not be used to reduce the swelling of bites or stings.
- Hyaluronidase should not be used for intravenous injections because the enzyme is rapidly inactivated.
- Furosemide, the benzodiazepines and phenytoin have been found to be incompatible with hyaluronidase.
- Anaphylactic-like reactions following retrobulbar block or intravenous injections have occurred, rarely.
- Hyaluronidase should not be applied directly to the cornea. It is not for topical use.
Efficacy and effect
Makes penetration of injection easy when subcutaneous injection, intramuscular injection or local anesthetics are injected under the skin to improves capability of absorbing excessive body fluid or blood in human organs.
! Before Use , dilute in 3-4 ml of 0.9% NaCl solution (saline)
Products containing hyaluronidase are intended for correcting unsuccessful results of beauty injections and for solving some other esthetic problems.
Main advantages
- High quality and safety.
- Provides a possibility to remove some part of filler after contour correction procedures.
- Efficiently removes some scar formations without surgical interference.
Description and composition
It is released in the form of a lyophilized powder in 5 ml. vials. Product is available for purchase in packages - 10 pieces in each. The active component is a depolymerizing enzyme hyaluronidase, an activity of 1500 c.u.
Product purpose
Liporase inj. is used in aesthetic medicine.
Indications to using the product:
- Overcorrection by fillers in contour plastics;
- Granulomas (nodular formations);
- Fibro-sclerotic form of cellulites.
Injections are made directly into the area of correction. Following the injection there starts the destruction of molecular compounds of hyaluronic acid. Shorter oligomers are injected naturally. The procedure result will be noticeable following 2 days.
Composition:
Depolymerizing enzyme hyaluronidase 1500 c.u. (activity is expressed in conditional units)
To Dissolve Filler:
- Draw 1ml of saline solution 0.9%.
- To dissolve more volume of filler, draw up 10ml of saline solution 0.9%.
- Inject the saline solution into the little bottle of Liporase until it's full.
- Mix it gently by rotating the Hyaluronidase bottle very gently.
- Draw back the mixed solution into the syringe.
- Inject it slowly into the filler where needs to be dissolved.
To maximise Lipodissolve injections. Same as above, but for fat dissolving injections, use 3ml of saline solution.
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